2025-08-24·8 min read·Mental Health

Schizophrenia Nursing Care for the NCLEX

Positive and negative symptoms, antipsychotic medications, and therapeutic nursing interventions.

Positive Symptoms (Excess)

  • Hallucinations (most common: auditory)
  • Delusions (paranoid, grandiose, persecutory)
  • Disorganized speech and behavior
  • Agitation

Negative Symptoms (Deficit)

  • Flat affect
  • Alogia (poverty of speech)
  • Avolition (lack of motivation)
  • Anhedonia (inability to feel pleasure)
  • Social withdrawal

Antipsychotic Medications

  • Typical (first-gen): Haloperidol - blocks dopamine. Monitor for EPS: dystonia, akathisia, tardive dyskinesia, neuroleptic malignant syndrome
  • Atypical (second-gen): Risperidone, olanzapine, quetiapine - fewer EPS, monitor for metabolic syndrome (weight gain, diabetes)
  • Clozapine: Treatment-resistant schizophrenia. Monitor WBC/ANC weekly - risk of agranulocytosis

Nursing Interventions

  • Do NOT argue with delusions - redirect, build trust
  • For hallucinations: "I don't hear the voices, but I understand they're real to you"
  • Maintain safety, consistent routine
  • Medication adherence is the biggest challenge

Learn more at Psychiatric Nursing cheat sheet and Psychiatric Medications deep dive.